Microbiome Studies: The Future Genesis of Life on Space


Microbiome research has illuminated the intricate relationships between microbes and their hosts, offering transformative potential in medicine, agriculture, and environmental science.

As technologies advance and ethical frameworks develop, the field stands poised to unlock new dimensions of microbial ecology and its applications in human and planetary health.

Microbiome Studies In Space

Understanding microbial dynamics beyond Earth as we know, humanity ventures into space for longer durations, understanding the behaviour of microorganisms in the unique environment of space is crucial.

The space microbiome, consisting of microbial communities in space habitats and their interactions with astronauts, has emerged as a significant area of research. These studies aim to ensure astronaut health, maintain spacecraft integrity, and explore the potential for life beyond Earth.

Microbiome studies in space are uncovering how microorganisms adapt to the extreme conditions of space and their implications for human health, spacecraft integrity, and the search for extra-terrestrial life.

As space exploration progresses, integrating microbiome management into mission planning will be essential for the success and sustainability of future space endeavours.

msrt microbiom in space 2

Picture-1. Microbiome – Microbial expedition over space.

Life Existence Over Space

The search for life beyond Earth is a multi-pronged approach. We’re constantly surveying the cosmos for planets that might be suitable for life, “exoplanets.” These planets should be located within a star’s habitable zone, where temperatures allow liquid water to exist on the surface, a key ingredient for life as we know it.

Thousands of exoplanets have already been discovered, and with every new telescope, our ability to find potentially life-supporting worlds increases.

Scientists are also looking for bio signatures, chemical signatures in a planet’s atmosphere that could be indicative of biological processes.

The presence of oxygen, for instance, would be a strong hint that life might exist. Analysing the atmospheres of distant planets is a rapidly developing field, and future missions may be able to provide more definitive answers.

Another avenue of exploration is the Search for Extra-Terrestrial Intelligence (SETI). By listening for radio signals from potential civilizations beyond Earth, SETI hopes to detect evidence of technological advancement.

While no definitive signal has been found yet, the vastness of space and the possibility of civilizations using different communication methods means the search continues.

The search for life beyond Earth is a testament to human curiosity and our desire to understand our place in the cosmos. With every new discovery, we inch closer to answering the age-old question;

  • Are we alone?

The answer, however it unfolds, is sure to be one of the greatest scientific breakthroughs of humanity

msrt microbiom in space 3

Picture-3. Life in space.

Microbiome In Space

Space may seem like a desolate void, but it’s teeming with tiny lifeforms – microbes! These resilient organisms, including bacteria and fungi, have been found not only surviving but thriving in the harsh environment of space.

Our fascination with space microbes began in the 1960s with experiments that exposed bacteria and spores to the harsh conditions of space. These studies revealed that some microbes can withstand the extreme cold, vacuum, and radiation found beyond Earth.

The International Space Station (ISS) itself has become a hotbed of microbial life. Astronauts bring their own unique microbiomes with them, and the ISS environment allows these microbes to adapt and evolve. Scientists are studying these space microbes to understand how they respond to microgravity and space radiation.

Some microbes have shown promise in breaking down waste and producing food, which could be crucial for sustaining human life on long-duration space missions.

The presence of microbes in space also raises interesting questions about the possibility of life on other planets. If life arose on Earth under extreme conditions, it could exist elsewhere in the universe as well.

Research Applications Over Microbes

Microbiome research in space offers exciting possibilities for furthering our understanding of space travel’s impact on human health and developing strategies for future missions. Here are some key areas of application:

  • Maintaining Astronaut Health: Spaceflight disrupts the delicate balance of microbes in the human body, potentially affecting immune function and overall health. Studying these changes allows researchers to develop strategies to mitigate negative effects, such as probiotic supplements or tailored diets.
  • Bioremediation and Waste Management: Microbes can be incredibly adept at breaking down organic waste. In closed-loop space habitats, microbes could play a crucial role in waste recycling and resource recovery, promoting mission sustainability.
  • Planetary Habitability: Studying how microbes adapt to the harsh environment of space can shed light on the potential for life on other planets. This knowledge could inform the search for extra-terrestrial life and the development of methods for detecting bio signatures on distant worlds.


The study of space microbiomes is a burgeoning field with significant implications for both astronaut health and our understanding of life beyond Earth. By understanding how microbes adapt to spaceflight, we can develop strategies to mitigate negative health effects on astronauts during long-duration missions.

Furthermore, space microbes themselves hold promise for bioremediation and resource management in closed space habitats. Ultimately, these tiny organisms may play a vital role in our endeavors to push the boundaries of space exploration.


  • Qin, J., et al. (2010). A human gut microbial gene catalogue established by metagenomic sequencing. Nature.
  • Turnbaugh, P.J., et al. (2007). The human microbiome project. Nature.
  • Zhou, Y., et al. (2020). The effect of antibiotic treatment on gut microbiota. Frontiers in Microbiology.
  • Lloyd-Price, J., et al. (2017). Multi-omics of the gut microbial ecosystem. Nature

Beğen  12
Meghachand Pantulu

Bharath University - Biotechnology , MoEP-Microbiome and Space Research Team (MSRT) Crew and MoEP Author.

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